News from BOINC Projects

Recent items from the news feeds of various BOINC projects.

[World Community Grid] Research Update from the MCM Team (February 2024)

We continue our work on characterising lung cancer biomarkers identified in the MCM1 project. This update focuses on a transcriptional corepressor TLE3.

View article · Fri, 16 Feb 2024 21:51:52 +0000

[YAFU] Aliquot sequence 2772150 has terminated!!!

Aliquot sequence 2772150 has terminated!!!

View article · Fri, 16 Feb 2024 18:36:25 +0000

[YAFU] Aliquot sequence 2771604 has terminated!!!

Aliquot sequence 2771604 has terminated!!!

View article · Thu, 15 Feb 2024 19:53:58 +0000

[RakeSearch] Processing of the square # 31 completed

Dear participants, processing of the square # 31 is fully completed! The square:

0 1 2 3 4 5 6 7 8 9 A B
1 2 0 4 5 3 8 9 A B 6 7
5 3 4 2 0 1 7 8 9 A B 6
B 7 9 8 A 6 5 1 3 2 4 0
A 6 8 7 9 B 0 5 1 3 2 4
9 B 7 6 8 A 4 0 5 1 3 2
6 8 A 9 B 7 1 3 2 4 0 5
4 5 3 1 2 0 B 6 7 8 9 A
3 4 5 0 1 2 9 A B 6 7 8
2 0 1 5 3 4 A B 6 7 8 9
7 9 B A 6 8 3 2 4 0 5 1
8 A 6 B 7 9 2 4 0 5 1 3

has 27472 diagonal transversals and 1037120685 orthogonal mates, like square # 9. And square #31 can be produced from square #9 by rows permutation, also!

Thank you for project attention, support and donation of CPU time!

View article · Thu, 15 Feb 2024 19:16:33 +0000

[World Community Grid] Research update from the OPN team (February 2024)

The Open Pandemics team has released new work units, which are targeting the DNA polymerase of cytomegalovirus.

View article · Wed, 14 Feb 2024 17:01:13 +0000

[] Discord channel for GPUGRID

Hi, I have created a discord channel for GPUGRID. It kind of duplicates this in some aspects but maybe people are more used to Discord. It is an additional channel that may help to build up the community. JOIN: GDF

View article · Tue, 13 Feb 2024 11:29:01 +0000

[TN-Grid] New experiment on Spinal muscular atrophy (SMA) from Mus musculus

We just started two experiments (gene expansion) on two different datasets (rnaseq, riboseq). There will be a total of about 140k workunits (2x tasks), each one relatively fast, distributed in batches.
If interested please follow the discussion here:

View article · Tue, 13 Feb 2024 09:56:35 +0000

[Gerasim@Home] Gerasim@home:

News from the BattleFields:
Batch Name: DS16x12
Total WUs in Batch: 78125000

Batch Progress12.2 %
ETA426.2 days

WUs completed: 9502000
WUs left: 68623000

View article · Mon, 12 Feb 2024 20:15:27 +0000

[YAFU] Aliquot sequence 106^33 has terminated!!!

Aliquot sequence 106^33 has terminated!!!

View article · Sun, 11 Feb 2024 09:42:24 +0000

[SRBase] New TF multiGPU apps deployed (issues fixed)

You need v28 to run it. There is only support for AMD and Nvidia cards.

To run more than 1 GPU you must have this cc_config:

<cc_config> <options> <use_all_gpus>1</use_all_gpus> </options> </cc_config>

View article · Sat, 3 Feb 2024 14:34:28 +0000

[SRBase] news update on multiGPU setup

Our BOINC wrappers were already prepared on running the config but we missed a file change a long time ago. With the hint of the user CallMeFoxie and testing of user DeleteNull we are now prepared to run such a config on windows and linux except Intel ARC cards.

The big update is planned on Friday this week.

View article · Wed, 31 Jan 2024 21:34:56 +0000

[PrimeGrid] Tour de Primes 2024

February is almost upon us, and with it, PrimeGrid's annual Tour de Primes. This is a month long event where all can earn special Tour de Primes badges and a lucky few will win the coveted Tour de Primes jerseys. More information can be found here.

View article · Wed, 31 Jan 2024 17:11:00 +0000

[Gerasim@Home] Gerasim@home:

Наконец-то  добавлены задания в достаточном количестве. 
На сколько их хватит? На неделю, или на месяц? Поехали!
Well, finally enough tasks have been added. How long will they last? 
For a week, or for a month? Go!
Computing with "Vaya Con Dios" - Nah neh nah

View article · Tue, 30 Jan 2024 05:24:28 +0000

[PrimeGrid] Unplanned outage

This afternoon PrimeGrid experienced an unplanned outage. For reasons unknown, the database locked up and started consuming 100% CPU on all 32 cores, while doing nothing at all. We proceeded cautiously, not wanting to risk damaging the database, and slowly shut down the system, checked the database, and brought everything back up. Everything is back to normal, and the servers are operating once again.

View article · Sat, 27 Jan 2024 00:49:20 +0000

[Universe@Home] Universe@Home future

The time has come to inform you about what will happen next with the Universe@Home project.

As you know, Krzysztof Belczyński was the initiator and lead scientist of the project - he was the head of our small team. His sudden passing caused a bit of chaos, which we are gradually trying to manage. Unfortunately, the latest changes in the application code that were being implemented also disappeared with him. For this reason, as well as the necessity to introduce changes to the application code that had been planned for some time, we have decided to temporarily suspend the generation of new WUs.

As of today, we already know that Universe@Home will not end - it is being taken under the wing of Prof. Tomasz Bulik ( Nevertheless, we must ask for your patience; at this moment, the most important thing is to manage the organizational and formal matters and to work on the changes in the code. This should take us two to three months.

I will keep you updated.

View article · Fri, 26 Jan 2024 18:40:08 +0000

[SIDock@home] Vote for the next target!

Dear all, we have obtained results for different targets of SARS-CoV-2. The computations continue, and we want to ask your opinion on the next target. You can vote for one of them until February 5th, 2024.

  • SARS-CoV-2 main protease (3CLpro) further studies

    This is a crucial therapeutic target against SARS-CoV-2. 3CLpro (cysteine protease; EC in particular is crucial for the cleavage of coronavirus polyproteins to form mature non-structural proteins that are themselves essential for viral replication mechanisms. We still need much more research on this target towards new more potent inhibitors.

  • Ebolavirus glycoprotein (GP)

    Ebola virus is a dangerous pathogen to humans and this target could be a perfect study case for PPI-type drug design scenario. The EBOV glycoprotein (GP) is the only virally expressed protein on the virion surface and is critical for attachment to host cells and catalysis of membrane fusion.

  • Swine acute diarrhea syndrome coronavirus (SADS-CoV PLpro)

    This target would enable us to study the design on multiple related viral targets. Swine acute diarrhea syndrome coronavirus (SADS-CoV), a newly emerging enteric coronavirus, is considered to be associated with swine acute diarrhea syndrome (SADS) which has caused significantly economic losses to the porcine industry. The pathogen indicates towards host-jump potential.

View article · Fri, 26 Jan 2024 12:36:20 +0000

[SRBase] phpmailer / email notifications issues fixed

There were a lot of notification issues since 14th while the project email account was blocked. A small change today fixed it including UOTD.

View article · Tue, 23 Jan 2024 17:17:36 +0000

[Amicable Numbers] Beta test of part 3 of the 10^21 search

Part 2 of the 10^21 search will be over some time in March this year, so it's time to start getting ready for part 3! I found a few bugs in the current GPU applications that needed to be fixed (CPU applications are fine).

To make sure everything works as intended, I will launch a small beta-test of the part 3 search by the end of this week. The new work units will require ~2.5-2.7 GB RAM on CPU, and the same amount of RAM on GPU (for GPU applications), so the minimum requirement for GPUs will be 3 GB RAM.

The purpose of the test is to confirm that all OS/CPU/GPU combinations work properly and confirm that 3 GB GPUs can process the new work units.

View article · Mon, 22 Jan 2024 20:15:18 +0000

[NumberFields@home] server maintenance

Just a heads up, the server was upgraded to the latest version of Ubuntu this morning.

The database seems to be crashing every so often with an error about exceeding max connections. Bear with me as we look into this.

View article · Fri, 19 Jan 2024 23:40:14 +0000

[YAFU] Aliquot sequence 2990736 has terminated!!!

Aliquot sequence 2990736 has terminated!!!

View article · Wed, 17 Jan 2024 19:35:27 +0000

[World Community Grid] Research update from the MCM team (January 2024)

We continue our work on characterizing lung cancer biomarkers identified in the MCM1 project. This update focuses on PCSK5, a gene associated with lung cancer survival and which shows differential expression across various cancer types.

View article · Tue, 16 Jan 2024 17:18:18 +0000

[Universe@Home] For memory of Krzysztof Belczyński

I met Krzysztof in the summer of 2014. It was then that Grzegorz Wiktorowicz found me and invited me to collaborate on a new scientific project. The reason they found me on the Internet was a problem with accessing the necessary computing power needed for the scientific research of these two scientists.
Soon after, the test server for the Universe@Home project was created - some of you may still remember it.

As soon as it turned out that the idea of using BOINC was a bullseye, Krzysztof offered me a more permanent collaboration, which I undertook with joy.
Few of us have the opportunity to work with scientists of this caliber.

We worked together for almost 10 years. About a month ago, we were discussing development possibilities, and Krzysztof was telling me about the publications being created based on our joint work (yes, there were supposed to be more than one!).

Unfortunately, today we will no longer be able to implement these plans...

As Krzysztof was a founder of the project, I don’t know yet what will happen next with our project. It's too early for any decisions, but whatever they may be - you will find out immediately. Krzysztof never forgot to mention the help our community provided him, and I am sure that we too will remember his trust in the power of the community...

View article · Tue, 16 Jan 2024 16:39:35 +0000

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