Recent items from the news feeds of various BOINC projects.

[Gerasim@Home] Gerasim@home:

View article · Sun, 26 Mar 2023 17:16:23 +0000

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[World Community Grid] SCC Project starts a new phase in their quest for curing childhood cancers

The SCC project has entered the next phase of the research and new workunits have been prepared for the BOINC restart.

View article · Wed, 22 Mar 2023 20:14:29 +0000

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[World Community Grid] Research update from the MCM team (March 2023)

The MCM team’s research into lung cancer biomarkers has identified 26 genes that are present with top scores across all the signature sizes considered. This update focuses on VAMP1, a gene linked to patient survival and differentially expressed in normal lung compared to lung cancer.

View article · Mon, 20 Mar 2023 17:42:52 +0000

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[WEP-M+2] 12-digit factor of P2203 has now been found by the project...

...405866 times - still no sign of any larger factors

View article · Sun, 19 Mar 2023 11:51:06 +0000

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[Yoyo@home] M Queens 27 additional workunits

We have to process some additional workunits. Some returned already.

View article · Sat, 18 Mar 2023 23:00:00 +0000

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[World Community Grid] Research update from the ARP team (March 2023)

A short update from the ARP team, including details about the changes they are making to their storage system.

View article · Wed, 15 Mar 2023 17:01:02 +0000

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[World Community Grid] Hardware Recovery Update

The website has been restarted and we are working on rebuilding the science database so BOINC can restart soon.

View article · Tue, 14 Mar 2023 18:24:07 +0000

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[Gerasim@Home] Gerasim@home:

View article · Tue, 14 Mar 2023 14:56:13 +0000

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[WEP-M+2] P2203:240000000 wu's (of 10000 trials each equiv.) processed!

Thanks to all the users. Please keep crunching!

View article · Thu, 9 Mar 2023 10:39:09 +0000

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[Einstein@home] News about Einstein@Home searches for radio and gamma-ray pulsars

Dear Einstein@Home volunteers,

read more

View article · Wed, 8 Mar 2023 09:37:15 +0000

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[PrimeGrid] International Women's Day Challenge on March 8th

Welcome back from Tour de Primes! We're kicking off March with a lightning round single-day challenge! Read on... The second challenge of the 2023 Series will be on International Women's Day, a global holiday celebrated annually on March 8 as a focal point in the women's rights movement, bringing attention to issues such as gender equality, reproductive rights, and violence and abuse against women. The challenge will be 1-day in duration and offered on the SGS-LLR application, beginning 08 March 15:00 UTC and ending 09 March 15:00 UTC. To participate in the Challenge, please select only the Sophie Germain Prime Search (LLR) project in your PrimeGrid preferences section. Nonplussed? Nostalgic? Nihilistic? Nervous? Newly inspired? Join the discussion at https://www.primegrid.com/forum_thread.php?id=10168

View article · Tue, 7 Mar 2023 02:04:09 +0000

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[Yoyo@home] M Queens 27 has finished

The M Queens subproject has finished last weekend. No more workunits are distributed. Now we are analyzing the results which are 8 GB of compressed data. Much thanks for your provided work.

View article · Sun, 5 Mar 2023 23:00:00 +0000

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[GPUGrid.net] ATM

Hello GPUGRID! You‘ve already noticed that a new app called “ATM” has been deployed with some test runs. We are working on its validation and deployment, so expect more jobs to come on this app soon. Let me briefly explain what this new app is about. The ATM application The new ATM application stands for Alchemical Transfer Method, a methodology Emilio Gallicchio et al. designed for absolute and relative binding affinity predictions. The ATM method allows us to estimate binding affinities for molecules against a specific protein, measuring the strength at which they bind. This methodology falls under the category of alchemical free energy calculation methods, where unphysical intermediate states are used to estimate the free energy of physical processes (such as protein-ligand binding). The benefits of ATM, when compared with other common free energy prediction methods (like the popular FEP), come from its simplicity, as it can be used with any forcefield and does not require a lot of expertise to make it work properly. Measuring experimental binding affinities between candidate molecules and the targeted protein is one of the first steps in drug discovery projects, but synthesizing molecules and performing experiments is expensive. Having the capacity to perform computational binding affinity predictions, particularly during drug lead optimization, is extremely beneficial. We are actively working now on testing and validating the ATM method so that we can start applying it to real drug discovery projects as soon as possible. Additionally, since these methods are usually applied to hundreds of molecules, it benefits a lot from the parallelization capabilities of GPUGRID, so if everything goes as expected, this could potentially send lots of work units. The ATM app is based on Python, similar to the PythonRL application, where we ship it with a specific python environment. Here are the two main references for the ATM method, for both absolute and relative binding affinity predictions: Absolute binding free energy estimation with ATM: https://arxiv.org/pdf/2101.07894.pdf Relative binding free energy estimation with ATM: https://pubs.acs.org/doi/10.1021/acs.jcim.1c01129 For now we are only able to send jobs to Linux machines but we are hoping to have a Windows version soon.

View article · Fri, 3 Mar 2023 10:39:46 +0000

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[SETI@home] Nebula progress report

Check out our latest newsletter: Final update.

View article · Fri, 3 Mar 2023 04:59:42 +0000

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[TN-Grid] Storage problem (again)

As all of you already know we are constantly struggling with our problematic storage. The University have bought a new one and they planned the moving procedure. The HPC cluster should be moved this Monday (March, 6th), the other resources will follow.
I will reasonably shut down the server when needed, I will tell you when as soon as I know the date. Meanwhile the work generator will be active just a few hours a day, so very few workunits will be available.
Thank you all for your understanding and patience.

View article · Thu, 2 Mar 2023 10:00:42 +0000

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[Milkyway@home] New N-Body Runs

Hello everyone,

The following are the new runs for N-Body:

de_nbody_02_27_2023_v182_pal5__data__1
de_nbody_02_27_2023_v182_pal5__data__2
de_nbody_02_27_2023_v182_pal5__data__3

These are our first runs of Palomar 5 with data from SDSS DR17.
Please let me know if there are any issues with these new runs.

Thanks,
Kevin

View article · Mon, 27 Feb 2023 19:45:26 +0000

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[Gerasim@Home] Gerasim@home:

View article · Sun, 26 Feb 2023 04:02:10 +0000

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[SIDock@home] BOINC merchandise by the Science Commons Initiative

Dear participants,

There is a wonderful new beginning started by the Science Commons Initiative. They launched a web store selling BOINC-related merchandise. SiDock@home is already on board :)

We support this idea and hope it will help more people to know about BOINC and get interested in BOINC projects! It will also contribute to the development of BOINC as 50% of the profits will go to the BOINC Development Fund (100% in special cases). Another 50% of the profit will go to the project as a donation.

With best wishes,
team of SiDock@home

View article · Thu, 23 Feb 2023 09:29:38 +0000

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[Gerasim@Home] Gerasim@home:

View article · Wed, 22 Feb 2023 05:04:02 +0000

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[Gerasim@Home] Gerasim@home:

Первая видеокарта в списке ускорителей вычислений. https://gerasim.boinc.ru/users/viewTopAccelerators.aspx

View article · Tue, 21 Feb 2023 00:21:00 +0000

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[Gerasim@Home] Gerasim@home:

View article · Mon, 20 Feb 2023 18:32:53 +0000

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