One of my machines has developed an issue with its graphics. It has an ASUS HD7850 card. It places an array of sets of four dark spots over about 30% of the screen area. The position of the spots changes, and sometimes the video attributes, colour, flashing etc. I have suspended GPU based projects on the machine. It is still quite readable now, but suspect a replacement will be required in the not too distant future. I'm just looking for some do's and don'ts in what to look for. Most of the "best graphics" sites I've looked at assume I am going to be seriously playing games, absolutely not the case with me. I want to be able to crunch with it.

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Wave upon wave of demented avengers march cheerfully out of obscurity into the dream.

The answer depends on which projects you want to do work for. For some projects (e.g. SETI) a recent nVidia will be best, while for others a recent AMD will be best. Take a look at each of your projects' forum and see what they say.

Okay, sods law being what it is, I'm sure the projects, (Seti, Einstein, Milky Way), on the machine will want both between them. The other projects on there do not use the GPU.

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Wave upon wave of demented avengers march cheerfully out of obscurity into the dream.

From memory all three projects have applications for both AMD & nVdia GPUs - but which family is better...
Sod Law rules

Make sure that once you've chosen your new card that you uninstall any remnants of old drivers and run something like display driver uninstall in safe mode to get rid of all stragglers. Else switching between brands can be a problem when a part of an old AMD driver is still on there.

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Will do. Thanks.

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Wave upon wave of demented avengers march cheerfully out of obscurity into the dream.

Okay, sods law being what it is, I'm sure the projects, (Seti, Einstein, Milky Way), on the machine will want both between them. The other projects on there do not use the GPU.

Those are quite different projects. SETI prefers high FP32/SP, MW prefers high FP64/DP while E@H seems to like cards that Mine well like AMD Polaris cards. E@H responds well to memory OCs, so like mining.