Is there anyway to let a project use just my GPU? I want my CPU working on 1 project the fulltime, but that project doesn't use the GPU. Is there a way to force a project to just use the GPU?

Assuming you are attached to a project or projects which has applications for your type of GPU:

Log into your account at the website for each of those projects. At each one, visit your project preferences page: edit your preferences to deselect 'Use CPU' at those projects.

That will prevent any new CPU work being requested or allocated: it is regarded as courteous to complete and report any CPU work already issued. Do remember that all GPU tasks require some fractional CPU time in support: the fraction needed varies wildly from project to project, application to application, GPU (type) to GPU (type).

I appreciate the response. I am on Rosetta's website in my preferences and not only do I not see the option to select 'Use CPU' the limited checkboxes I have are non-responsive.

I am clearing all projects before limiting my focus to a single project. I know the work is important to all and don't want to leave pieces unfinished.

http://boinc.bakerlab.org/rosetta/prefs.php?subset=project is where you want to be. You need to click 'edit preferences' (at foot of list) to deselect CPU - it worked for me. Though I would have expected to have seen similar checkboxes for deselecting the different types of supported GPU, too.

Edit - I don't see any sign that Rosetta supports GPU crunching at either https://boinc.bakerlab.org/rosetta/apps.php or https://boinc.berkeley.edu/projects.php

Also, do know that GPU apps use the CPU. The application runs on the CPU, as it does all of the translating of the data into kernels that the GPU can calculate, and transport this data to the GPU, then transport the calculated results back and save them to disk.

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Rosetta is a CPU only project.