Using [this thread on the BOINC forums]:
"Hello there. I am totally blind and I use a text to speech synthesiser which reads out loud what is on the screen. I upgraded to the latest version of boinc just today, and I find I'm unable to use the new interface because you need to click on pictures and graphics and such in order to get to the various areas of the program. I'd really, really really really like to get the old interface back. How do I do this? I do not currently have any sighted assistance who can help me. I really wana be able to continue participating in boinc project, but I fear that boinc's interface will become more unfriendlier to blind users. Please Please help if you can."
The BOINC Simple GUI could use buttons with text on them that can be read by speech programs.